MLN4760
Catalogue number:
CAY31327-1 mg
Supplier:
Size:
1 mg
Product is available in:
£137.00
Estimated delivery Thu 30 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
305335-31-3
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C19H23Cl2N3O4
Molecular Weight:
428.3
Alternative Names:
n-[(1s)-1-
Product Description:
An ACE2 inhibitor (IC50 = 0.44 nM); selective for ACE2 over ACE and CPDA (IC50s = >100 and 27 µM, respectively); inhibits ACE2 hydrolysis of angiotensin I in vitro at 1 µM; inhibits the protein-protein interaction between ACE2 and the SARS-CoV-2 spike glycoprotein; inhibits exogenous recombinant ACE2-induced prevention of angiotensin II-induced hypertension in mice