AA-861
Catalogue number:
CAY13263-1 mg
Supplier:
Size:
1 mg
Product is available in:
£437.00
Estimated delivery Fri 1 May
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
80809-81-0
Purity:
≥95%
Formulation:
A solid
Molecular Formula:
C21H26O3
Molecular Weight:
326.4
Alternative Names:
2-(12-hydroxy-
Product Description:
A 5-LO inhibitor (IC50 = 0.8 µM); >100-fold selective for 5-LO over 12-LO and COX; inhibits A23187-induced production of 5-HETE and LTB4 (IC50s = 0.03 and 0.08 µM, respectively) in isolated rat peritoneal macrophages; reduces carrageenan-induced paw edema, pleurisy, and cell infiltration in rats at 80 mg/kg; reduces ovalbumin-induced bronchoconstriction in an ovalbumin-sensitized guinea pig model of experimental allergic asthma at 20 mg/kg