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Evocalcet

Catalogue number:
CAY33346-1 mg
Supplier:
Size:
1 mg
Product is available in:
  • UK
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£88.00 Estimated delivery Wed 10 Jun
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

870964-67-3

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Formula:

C24H26N2O2

Molecular Weight:

374.47552

Alternative Names:

4-[(3s)-3-[[(1r)-1-(1-naphthalenyl)ethyl]amino]-1-pyrrolidinyl]-benzeneacetic acid, khk7580, mt-4580

Product Description:

A CaSR agonist; induces intracellular calcium release in HEK293 cells expressing human CaSR (EC50 = 92.7 nM); reduces serum levels of PTH and calcium at 0.3 and 0.1 mg/kg, respectively, in non-nephrectomized and 5/6 nephrectomized rats; reduces serum levels of PTH without inducing emesis in marmosets at 0.3 and 0.5 mg/kg