DAPTA (acetate)
Catalogue number:
CAY33339-5 mg
Supplier:
Size:
5 mg
Product is available in:
£103.00
Estimated delivery Tue 6 Jan
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C35H56N10O15 • XC2H4O2
Molecular Weight:
856.87754
Alternative Names:
d-alanyl-l-
Product Description:
A CCR5 receptor antagonist; inhibits CD4-dependent binding of HIV-1Ba-L and HIV-1CM235 gp120 envelope proteins to CCR5 (IC50s = 0.06 and 0.32 nM, respectively); reduces marble burying and repetitive behavior, as well as decreases brain levels of IL-6, IL-9, and IL-17A, in the BTBR T+ Itpr3tf/J mouse model of ASD at 0.1 mg/kg; reduces LPS-induced microglial activation and astrocyte hypertrophy in the dentate gyrus in a rat model of chronic neuroinflammation