DAPTA (acetate)
Catalogue number:
CAY33339-5 mg
Supplier:
Size:
5 mg
Product is available in:
£103.00
Estimated delivery Wed 25 Feb
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C35H56N10O15 • XC2H4O2
Molecular Weight:
856.87754
Alternative Names:
d-alanyl-l-
Product Description:
A CCR5 receptor antagonist; inhibits CD4-dependent binding of HIV-1Ba-L and HIV-1CM235 gp120 envelope proteins to CCR5 (IC50s = 0.06 and 0.32 nM, respectively); reduces marble burying and repetitive behavior, as well as decreases brain levels of IL-6, IL-9, and IL-17A, in the BTBR T+ Itpr3tf/J mouse model of ASD at 0.1 mg/kg; reduces LPS-induced microglial activation and astrocyte hypertrophy in the dentate gyrus in a rat model of chronic neuroinflammation