HT-2157
Catalogue number:
CAY33848-25 mg
Supplier:
Size:
25 mg
Product is available in:
£333.00
Estimated delivery Wed 10 Jun
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
303149-14-6
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C21H13F3N2O
Molecular Weight:
366.336009
Alternative Names:
1,3-dihydro-1-
Product Description:
A GAL3 receptor antagonist (Ki = 17 nM); selective for GAL3 over GAL1 and GAL2 (Kis = >10 µM for both); induces apoptosis in various cell types, including HL-60 leukemia and BV-2 murine microglial cells, as well as isolated human PBMCs at 10 µM; decreases operant alcohol, sucrose, and saccharin self-administration in rats at 30 mg/kg; increases drinking in the Vogel punished drinking task and reduces immobility time in the forced swim test in rats, indicating anxiolytic- and antidepressant-like activities, respectively, at 3 and 10 mg/kg