ZM 449829
Catalogue number:
CAY32820-25 mg
Supplier:
Size:
25 mg
Product is available in:
£451.00
Estimated delivery Tue 16 Dec
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
4452-06-6
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Formula:
C13H10O
Molecular Weight:
182.2179
Alternative Names:
1-(2-naphtha
- MSDS: View or download
Product Description:
An inhibitor of JAK3 (IC50 = 0.158 µM) and a degradation product of ZM 329923; selective for JAK3 over EGFR and JAK1 (IC50s = 10 and 19.95 µM, respectively) but does inhibit TGM2 and FXIIIa (IC50s = 0.005 and 0.006 µM, respectively); decreases the formation of CSC within MCF-7-derived mammospheres; decreases migration of, and colony formation by, MCF-7 cells at 10 µM; inhibits formation of replication vacuoles in C. burnetii-infected HeLa and THP-1 cells at 10 µM