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Camptothecin

Catalogue number:
CAY11694-50 mg
Supplier:
Size:
50 mg
Product is available in:
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£37.00 Estimated delivery Tue 14 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

7689-03-4

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Formula:

C20H16N2O4

Molecular Weight:

348.4

Alternative Names:

(4s)-4-ethyl-4-hydroxy-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4h,12h)-dione, mag-cpt, nsc 94600

Product Description:

A cytotoxic, quinoline alkaloid that inhibits the DNA enzyme topoisomerase I (Top I) by binding the Top1-DNA cleavage complex and inducing DNA-strand breaks; has strong anti-tumor activity and induces DNA damage at concentrations as low as 51 nM in whole cells and 12 nM in isolated nuclei in in vitro assays