Ganglioside GM1 (ovine) (ammonium salt)

Name: Ganglioside GM1 (ovine) (ammonium salt)
Brand: Cayman Chemical
SKU: CBSKU_100922225
Price: 3758 GBP
Availability: InStock

Catalogue number:

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CAY31549-50 mg

Supplier:

Cayman Chemical

Size:

50 mg

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£3758.00

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This product is for research use only and is not for human consumption or therapeutic use.

CAS Number:

1007119-81-4

Purity:

≥98%

Formulation:

A solid

Molecular Formula:

C73H130N3O31 • NH4 (for stearoyl)

Molecular Weight:

1563.9

Alternative Names:

1-o-[o-β-d-galactopyranosyl-(1→3)-o-2-(acetylamino)-2-deoxy-β-d-galactopyranosyl-(1→4)-o-[n-acetyl-α-neuraminosyl-(2→3)]-o-β-d-galactopyranosyl-(1→4)-β-d-glucopyranosyl]-ceramide, monoammon

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Product Description:

A ganglioside; enriched in lipid rafts; associates with growth factor receptors and is required for TrkA expression on the cell surface; interacts with other proteins to increase calcium influx, affecting various calcium-dependent processes, including inducing neuronal outgrowth during differentiation; acts as a receptor for cholera toxin and the heat-labile enterotoxin from E. coli; accumulates in neurons in ganglioside GM1 gangliosidosis; levels are decreased in the substantia nigra pars compacta in postmortem brain from patients with Parkinson’s disease