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IL-4 Inhibitor

Catalogue number:
CAY32548-10 mg
Supplier:
Size:
10 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£664.00 Estimated delivery Wed 18 Feb
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1332184-63-0

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Formula:

C18H12FN3O2

Molecular Weight:

321.305303

Alternative Names:

2-amino-4-(3,4-dihydroxyphenyl)-6-(4-fluorophenyl)-3-pyridinecarbonitrile

Product Description:

An IL-4 inhibitor; binds to IL-4 (Kd = 1.8 µM); inhibits IL-4 activity in a cell-based reporter assay (EC50 = 1.81 µM); selective for IL-4 over IL-13 (EC50 = 18.2 µM); inhibits IL-4-induced STAT6 phosphorylation in THP-1 monocytes (EC50 = 3.1 µM)