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GLX-351322

Catalogue number:
CAY31523-5 mg
Supplier:
Size:
5 mg
Product is available in:
  • UK
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£121.00 Estimated delivery Wed 15 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

835598-94-2

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Formula:

C21H25N3O5S

Molecular Weight:

431.50642

Alternative Names:

2-[[2-[4-(2-furanylcarbonyl)-1-piperazinyl]acetyl]amino]-5,6-dihydro-4h-cyclopenta[b]thiophene-3-carboxylic acid, ethyl ester

Product Description:

A NOX4 inhibitor (IC50 = 5 µM); selective for NOX4 over NOX2 (IC50 = 40 µM); reduces glucose-induced production of ROS and cytotoxicity in isolated human pancreatic islets at 10 µM; decreases blood glucose levels in an intravenous glucose tolerance test in mice fed a high-fat diet at an estimated 3.8 mg/kg per day