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BIMU 8

Catalogue number:
CAY30964-1 mg
Supplier:
Size:
1 mg
Product is available in:
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£56.00 Estimated delivery Wed 15 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

134296-40-5

Purity:

≥98%

Formulation:

A solid

Molecular Formula:

C19H26N4O2 • HCl

Molecular Weight:

378.89614

Alternative Names:

2,3-dihydro-n-[(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]-3-(1-methylethyl)-2-oxo-1h-benzimidazole-1-carboxamide, monohydrochloride

Product Description:

A 5-HT4 receptor agonist (Ki = 69 nM); also binds 5-HT3 receptors (Ki = 0.36 nM); stimulates cAMP formation in primary mouse embryonic colliculi neurons (EC50 = 72 nM); induces acetylcholine release in the rat frontal cortex at 30, 40, and 60 nmol/animal; increases postprandial antral and colonic motility in conscious dogs at 0.1, 0.3, and 1 mg/kg; increases the latency to withdraw in the paw pressure test in rats at 20 mg/kg