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2',2'-Difluoro-2'-deoxyuridine

Catalogue number:
CAY11689-10 mg
Supplier:
Size:
10 mg
Product is available in:
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£367.00 Estimated delivery Wed 25 Mar
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

114248-23-6

Purity:

≥95%

Formulation:

A crystalline solid

Molecular Formula:

C9H10F2N2O5

Molecular Weight:

264.2

Alternative Names:

2′-deoxy-2′,2′-difluoro-uridine, dfdu

Product Description:

An active metabolite of gemcitabine; formed by deamination of gemcitabine by cytidine deaminase in the liver; cytotoxic to HepG2 and A549 cancer cells (IC50s = 3.13 and 3.92 µM, respectively); enhances radiation-induced cell death of ECV304 and NCI H292 cells from 10-100 µM