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Alarelin (acetate)

Catalogue number:
CAY30993-250 mg
Supplier:
Size:
250 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£930.00 Estimated delivery Fri 15 May
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CAS Number:

79561-22-1

Purity:

≥98%

Molecular Weight:

1287.42308

Alternative Names:

6-d-alanine-9-(n-ethyl-l-prolinamide)-1-9-luteinizing hormone-releasing factor (swine), diacetate, [d-ala6, des-gly10]gnrh-ethylamide, des-gly gnrh, pglu-hwsyalrp-nhet

Product Description:

A peptide agonist of GnRH; binds to GnRHR (Kd = 0.2 nM); decreases GnRH and GnRHR expression in the preoptic area and pMBH, respectively, of ovariectomized estradiol-treated rats at 6 ng, i.c.v., indicating an ultrashort negative feedback loop; induces desensitization in the pituitary and decreases serum estradiol levels and ovarian and uterine weight in neonatal and adult female rats; reduces tumor growth in an HEC-1-B mouse xenograft model at 20, 40, and 80 µg/mg