YM-90K (hydrochloride hydrate)
Catalogue number:
CAY30683-5 mg
Supplier:
Size:
5 mg _$$_
Product is available in:
£234.00
Estimated delivery Tue 21 May
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
309.7
Alternative Names:
1,4-dihydro-6-(1h-imidazol-1-yl)-7-nitro-2,3-quinoxalinedione, monohydrochloride, hydrate
- Data sheet: View or download
- MSDS: View or download
Product Description:
An AMPA receptor antagonist (Ki = 0.084 µM in a radioligand binding assay using rat brain membranes); selective for AMPA over kainate, NMDA-sensitive glutamate, and strychnine-insensitive glycine receptors (Kis = 2.2, >100, and 37 µM, respectively); intrastriatal administration inhibits AMPA-induced decreases in ChAT activity in rat striatum ex vivo; inhibits audiogenic seizures in susceptible DBA/2 mice with a minimum effective dose of 3 mg/kg, i.p.; intravenous infusion reduces infarct size in a rat model of focal cerebral ischemia induced by thrombotic MCAO in rats at 20 mg/kg per hour for 4 hours
Storage Temperature:
-20°C