YM-90K (hydrochloride hydrate)
Catalogue number:
CAY30683-1 mg
Supplier:
Size:
1 mg _$$_
Product is available in:
£81.00
Estimated delivery Tue 9 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
309.7
Alternative Names:
1,4-dihydro-6-(1h-imidazol-1-yl)-7-nitro-2,3-quinoxalinedione, monohydrochloride, hydrate
- Data sheet: View or download
- MSDS: View or download
Product Description:
An AMPA receptor antagonist (Ki = 0.084 µM in a radioligand binding assay using rat brain membranes); selective for AMPA over kainate, NMDA-sensitive glutamate, and strychnine-insensitive glycine receptors (Kis = 2.2, >100, and 37 µM, respectively); intrastriatal administration inhibits AMPA-induced decreases in ChAT activity in rat striatum ex vivo; inhibits audiogenic seizures in susceptible DBA/2 mice with a minimum effective dose of 3 mg/kg, i.p.; intravenous infusion reduces infarct size in a rat model of focal cerebral ischemia induced by thrombotic MCAO in rats at 20 mg/kg per hour for 4 hours
Storage Temperature:
-20°C