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CHM-1

Catalogue number:
CAY27647-10 mg
Supplier:
Size:
10 mg
Product is available in:
  • UK
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  • Europe
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  • Rest of World
£180.00 Estimated delivery Wed 24 Dec
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

154554-41-3

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Formula:

C16H10FNO3

Molecular Weight:

283.253943

Alternative Names:

6-(2-fluorophenyl)-1,3-dioxolo[4,5-g]quinolin-8(5h)-one, nsc 656158

Product Description:

An inhibitor of tubulin polymerization (IC50 = 0.68 µM); inhibits chochicine tubulin binding at 5 µM; inhibits the growth of K562, NCI H226, HCT116, OVCAR-3, RXF 393L, SK-MEL-5, SF-268, and SF-295 cancer cells (mean GI50 = 130 nM); induces apoptosis in HA22T hepatocellular carcinoma cells; reduces tumor volume and increases survival in an HA22T mouse xenograft model at 10 mg/kg