£387.00
Estimated delivery Mon 12 Jan
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
2400954-16-5
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C11H10IN5O2
Molecular Weight:
371.13407
Alternative Names:
methyl 4-amino-6-
- MSDS: View or download
Product Description:
A cGAS inhibitor (IC50 = 0.45 µM); reduces DNA-, but not Sendai virus-, induced IRF3 dimerization in THP-1 cells, indicating cGAS pathway selectivity; selective for cGAS over TLRs at 50 µM; decreases IFN-stimulatory DNA-induced IFN-β production in THP-1 cells at 10, 30, and 100 µM