Norcantharidin
Catalogue number:
CAY28457-1 g
Supplier:
Size:
1 g
Product is available in:
£46.00
Estimated delivery Wed 15 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
29745-04-8
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Formula:
C8H8O4
Molecular Weight:
168.14672
Alternative Names:
(3ar,4s,7r,
Product Description:
A PP1 and PP2A inhibitor (IC50s = 9 and 3 µM, respectively); induces cell cycle arrest at the G2/M phase and apoptosis in HepG2, Hep3B, and Huh7 human hepatoma cell lines at 5 µg/ml; reduces angiogenesis in a chick chorioallantoic membrane assay at 500-5,000 µg/ml; inhibits growth in a panel of nine human cancer cell lines (GI50s = 30-64 µM); reduces tumor growth in a GBC-SD mouse xenograft model at 28 mg/kg