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JBSNF-000088

Catalogue number:
CAY29920-250 mg
Supplier:
Size:
250 mg
Product is available in:
  • UK
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  • Europe
  • USA
  • Rest of World
£79.00 Estimated delivery Wed 24 Dec
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

7150-23-4

Purity:

≥98%

Formulation:

A solid

Molecular Formula:

C7H8N2O2

Molecular Weight:

152.1507

Alternative Names:

6-methoxy-3-pyridinecarboxamide, 6-methoxynicotinamide, nsc 70628

Product Description:

An inhibitor of NMMT (IC50s = 1.8, 2.8, and 5 µM for human, monkey, and mouse NNMT, respectively); inhibits NNMT and reduces MNA levels in U2OS and 3T3L1 cells (IC50s = 1.6 and 6.3 µM, respectively); reduces visceral WAT, MNA levels, body weight, fed blood glucose levels, and plasma and liver triglyceride levels, and improves oral glucose tolerance in a mouse model of DIO; also improves glucose tolerance, without affecting body weight, in the ob/ob and db/db mouse models of insulin resistance and diabetes, respectively