Fenobam (hydrate)
Catalogue number:
CAY29759-1 mg
Supplier:
Size:
1 mg
Product is available in:
£46.00
Estimated delivery Mon 20 Apr
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
63540-28-3
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C11H11ClN4O2 • H2O
Molecular Weight:
284.69878
Alternative Names:
n-(3-chloro
Product Description:
A noncompetitive antagonist and inverse agonist of mGluR5 that binds to an allosteric site; inhibits quisqualate-induced intracellular calcium mobilization in HEK293 cells expressing the human receptor (IC50 = 58 nM); inhibits basal activity of mGluR5 in a cell-based assay (IC50 = 84 nM); reduces stress-induced hyperthermia in mice at 10 and 30 mg/kg; increases drinking time in the Vogel conflict test in rats at 30 mg/kg; induces analgesia in the formalin test in mice at 30 mg/kg