12-keto Lithocholic Acid
Catalogue number:
CAY29547-25 mg
Supplier:
Size:
25 mg
Product is available in:
£299.00
Estimated delivery Wed 29 Jul
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
5130-29-0
Purity:
≥98%
Formulation:
A solid
Molecular Formula:
C24H38O4
Molecular Weight:
390.6
Alternative Names:
(3α,5β)-3-hydroxy-12-oxo-cholan-24-oic acid, 12-keto lca, 12-keto lithocholate, 12-klca, 12-oxo lca, 12-oxo lithocholate, 12-oxo lithocholic acid
Product Description:
A metabolite of DCA; fecal levels are elevated in rats fed a diet supplemented with cholic acid or DCA compared with rats fed a control diet or a diet supplemented with cholesterol, HDCA, or LCA; activates the human PXR (EC50 = 31.3 µM in a cell-based transactivation assay); levels are increased in duodenal bile from patients with type 2 diabetes