Alves, C.L., Elias, D., Lyng, M., Bak, M., Kirkegaard, T., Lykkesfeldt, A.E. and Ditzel, H.J. (2016). High CDK6 Protects Cells from Fulvestrant-Mediated Apoptosis and is a Predictor of Resistance to Fulvestrant in Estrogen Receptor–Positive Metastatic Breast Cancer. Clinical Cancer Research, [online] 22(22), pp.5514–5526. Available at: https://clincancerres.aacrjournals.org/content/22/22/5514 [Accessed 20 Feb. 2020].
Product: Ingenio Electroporation Solution
• Cell type: MCF-7 & T47D
• Nucleic acid: siRNA
• Application: Gene knockdown
Basiorka, A.A., McGraw, K.L., De Ceuninck, L., Griner, L.N., Zhang, L., Clark, J.A., Caceres, G., Sokol, L., Komrokji, R.S., Reuther, G.W., Wei, S., Tavernier, J. and List, A.F. (2016). Lenalidomide Stabilizes the Erythropoietin Receptor by Inhibiting the E3 Ubiquitin Ligase RNF41. Cancer Research, [online] 76(12), pp.3531–3540. Available at: https://www.ncbi.nlm.nih.gov/pubmed/27197154 [Accessed 20 Feb. 2020].
Product: Ingenio Electroporation Solution
• Cell type: UT7
• Nucleic acid: shRNA-encoding plasmid DNA
• Application: Gene knockdown
Buren, C., Tu, G., Parsons, M.P., Sepers, M.D. and Raymond, L.A. (2016). Influence of cortical synaptic input on striatal neuronal dendritic arborization and sensitivity to excitotoxicity in corticostriatal coculture. Journal of Neurophysiology, 116(2), pp.380–390. Availlable at: https://pubmed.ncbi.nlm.nih.gov/27121581-influence-of-cortical-synaptic-input-on-striatal-neuronal-dendritic-arborization-and-sensitivity-to-excitotoxicity-in-corticostriatal-coculture/ [Accessed 2 March. 2020].
Product: Ingenio Electroporation Solution
• Cell type: Striatal neurons (mouse, primary)
• Nucleic acid: Plasmid DNA
• Application: Electroporation
Busch, J.I., Unger, T.L., Jain, N., Tyler Skrinak, R., Charan, R.A. and Chen-Plotkin, A.S. “Increased Expression of the Frontotemporal Dementia Risk Factor TMEM106B Causes C9orf72-Dependent Alterations in Lysosomes.” Human Molecular Genetics, vol. 25, no. 13, 1 July 2016, pp. 2681–2697. Available at: www.ncbi.nlm.nih.gov/pubmed/27126638, 10.1093/hmg/ddw127. [Accessed 20 Feb. 2020].
Product: Ingenio Electroporation Solution
• Cell type: Cortical neurons (E18 mouse, primary) & Hippocampal neurons (E18 mouse)
• Nucleic acid: Plasmid DNA
• Application: Electroporation
Cui, C., Ye, X., Chopp, M., Venkat, P., Zacharek, A., Yan, T., Ning, R., Yu, P., Cui, G. and Chen, J. (2016). miR-145 Regulates Diabetes-Bone Marrow Stromal Cell-Induced Neurorestorative Effects in Diabetes Stroke Rats. Stem Cells Translational Medicine, [online] 5(12), pp.1656–1667. Available at: https://www.ncbi.nlm.nih.gov/pubmed/27460851 [Accessed 20 Feb. 2020].
Product: Ingenio Electroporation Solution
• Cell type: BMSC
• Nucleic acid: miRNA
• Application: Gene knockdown
Harris, L., McFarlane-Majeed, L., Campos-León, K., Roberts, S. and Parish, J.L. (2017). The Cellular DNA Helicase ChlR1 Regulates Chromatin and Nuclear Matrix Attachment of the Human Papillomavirus 16 E2 Protein and High-Copy-Number Viral Genome Establishment. Journal of Virology, [online] 91(1). Available at: https://jvi.asm.org/content/91/1/e01853-16 [Accessed 20 Feb. 2020].
Product: Ingenio Electroporation Solution
• Cell type: C-33 A
• Nucleic acid: siRNA
• Application: Gene knockdown and electroporation
Heindryckx, F., Binet, F., Ponticos, M., Rombouts, K., Lau, J., Kreuger, J. and Gerwins, P. (2016). Endoplasmic reticulum stress enhances fibrosis through IRE1α‐mediated degradation of miR‐150 and XBP‐1 splicing. EMBO Molecular Medicine, 8(7), pp.729–744.Available at: https://www.embopress.org/doi/full/10.15252/emmm.201505925 [Accessed 2 March. 2020].
Product: Ingenio Electroporation Solution
• Cell type: HFL1
• Nucleic acid: siRNA
• Application: Electroporation
Kuny, C.V. and Kalejta, R.F. (2016). Human Cytomegalovirus Can Procure Deoxyribonucleotides for Viral DNA Replication in the Absence of Retinoblastoma Protein Phosphorylation. Journal of Virology, [online] 90(19), pp.8634–8643. Available at: https://jvi.asm.org/content/90/19/8634 [Accessed 20 Feb. 2020].
Product: Ingenio Electroporation Solution
• Cell type: NHDF
• Nucleic acid: siRNA
• Application: Electroporation
Li, Q., Wennborg, A., Aurell, E., Dekel, E., Zou, J.-Z., Xu, Y., Huang, S. and Ernberg, I. (2016). Dynamics inside the cancer cell attractor reveal cell heterogeneity, limits of stability, and escape. Proceedings of the National Academy of Sciences of the United States of America, [online] 113(10), pp.2672–2677. Available at: https://www.ncbi.nlm.nih.gov/pubmed/26929366 [Accessed 20 Feb. 2020].
Product: Ingenio Electroporation Solution
• Cell type: RAEL
• Nucleic acid: shRNA & Plasmid DNA
• Application: Gene knockdown and gene/protein expression
Mann, B.J., Balchand, S.K. and Wadsworth, P. (2017). Regulation of Kif15 localization and motility by the C-terminus of TPX2 and microtubule dynamics. Molecular Biology of the Cell, 28(1), pp.65–75.Available at: https://pubmed.ncbi.nlm.nih.gov/27852894-regulation-of-kif15-localization-and-motility-by-the-c-terminus-of-tpx2-and-microtubule-dynamics/ [Accessed 2 March. 2020].
Product: Ingenio Electroporation Solution
• Cell type: LLC-PK1
• Nucleic acid: siRNA
• Application: Gene knockdown
Morris, V.A., Cummings, C.L., Korb, B., Boaglio, S. and Oehler, V.G. (2016). Deregulated KLF4 Expression in Myeloid Leukemias Alters Cell Proliferation and Differentiation through MicroRNA and Gene Targets. Molecular and Cellular Biology, [online] 36(4), pp.559–573. Available at: https://www.ncbi.nlm.nih.gov/pubmed/26644403 [Accessed 20 Feb. 2020].
Product: Ingenio Electroporation Solution
• Cell type: Jurkat, THP-1 & K562
• Nucleic acid: siRNA
• Application: Gene knockdown
Qi, L., Jafari, N., Li, X., Chen, Z., Li, L., Hytönen, V.P., Goult, B.T., Zhan, C.-G. and Huang, C. (2016). Talin2-mediated traction force drives matrix degradation and cell invasion. Journal of Cell Science, [online] 129(19), pp.3661–3674. Available at: https://www.ncbi.nlm.nih.gov/pubmed/27694340 [Accessed 20 Feb. 2020].
Product: Ingenio Electroporation Solution
• Cell type: U2OS
• Nucleic acid: Plasmid DNA
• Application: Gene/protein expression
Surve, C.R., To, J.Y., Malik, S., Kim, M. and Smrcka, A.V. (2016). Dynamic regulation of neutrophil polarity and migration by the heterotrimeric G protein subunits Gαi-GTP and Gβγ. Science Signaling, 9(416), pp.ra22–ra22.Available at: https://pubmed.ncbi.nlm.nih.gov/26905427-dynamic-regulation-of-neutrophil-polarity-and-migration-by-the-heterotrimeric-g-protein-subunits-gi-gtp-and-g/ [Accessed 2 March. 2020].
Product: Ingenio Electroporation Solution
• Cell type: HL-60
• Nucleic acid: Plasmid DNA
• Application: Gene/protein expression
Thangaraj, M.P., Furber, K.L., Gan, J.K., Ji, S., Sobchishin, L., Doucette, J.R. and Nazarali, A.J. (2017). RNA-binding Protein Quaking Stabilizes Sirt2 mRNA during Oligodendroglial Differentiation. Journal of Biological Chemistry, [online] 292(13), pp.5166–5182. Available at: https://www.jbc.org/content/292/13/5166.full [Accessed 20 Feb. 2020].
Product: Ingenio Electroporation Solution
• Cell type: Oligodendrocytes (primary, mouse)
• Nucleic acid: Plasmid DNA
• Application: Gene/protein expression
Valsecchi, R., Coltella, N., Belloni, D., Ponente, M., Ten Hacken, E., Scielzo, C., Scarfò, L., Bertilaccio, M.T.S., Brambilla, P., Lenti, E., Martinelli Boneschi, F., Brendolan, A., Ferrero, E., Ferrarini, M., Ghia, P., Tonon, G., Ponzoni, M., Caligaris-Cappio, F. and Bernardi, R. (2016). HIF-1α regulates the interaction of chronic lymphocytic leukemia cells with the tumor microenvironment. Blood, [online] 127(16), pp.1987–1997. Available at: https://www.ncbi.nlm.nih.gov/pubmed/26825709 [Accessed 20 Feb. 2020].
Product: Ingenio Electroporation Solution
• Cell type: CLL & B-CLL
• Nucleic acid: Oligo
• Application: Primary cell electroporation
Willerslev-Olsen, A., Krejsgaard, T., Lindahl, L.M., Litvinov, I.V., Fredholm, S., Petersen, D.L., Nastasi, C., Gniadecki, R., Mongan, N.P., Sasseville, D., Wasik, M.A., Bonefeld, C.M., Geisler, C., Woetmann, A., Iversen, L., Kilian, M., Koralov, S.B. and Odum, N. (2016). Staphylococcal enterotoxin A (SEA) stimulates STAT3 activation and IL-17 expression in cutaneous T-cell lymphoma. Blood, [online] 127(10), pp.1287–1296. Available at: https://ashpublications.org/blood/article/127/10/1287/34951/Staphylococcal-enterotoxin-A-SEA-stimulates-STAT3 [Accessed 20 Feb. 2020].
Product: Ingenio Electroporation Solution
• Cell type: T cells
• Nucleic acid: siRNA
• Application: Gene knockdown & primary cell electroporation