For over a decade, Axol Bioscience have provided high-quality human induced pluripotent stem cells (iPSCs) designed for neuroscience, cardiovascular, and pain and sensation studies, all customisable to meet your specific biomedical research needs.
Axol’s iPSC catalogue features a wide range of neuronal cell types such as cortical excitatory neurons, striatal neurons, cortical inhibitory interneurons, sensory neurons and motor neurons. Other available cell types are neuroinflammatory cells (microglia and astrocytes), cardiac cells (atrial and ventricular cardiomyocytes) and muscle cells (skeletal myotubes).
Benefits of using axoCells
- Customise to specific cell types
- Ideal for high-throughput screening
- Produced under stringent quality control
- Avoid any ethical concerns
- Comprehensive support and protocols
| Cell type available | Description | Manfacture time* |
|---|---|---|
| Cortical excitatory neurons | Ideal for use in in vitro neuroscience models including AD. Frequently used in co-culture models with other neuronal and neuroinflammatory cells. Supplied as neural stem cells (NSCs) with maturation to cortical excitatory neurons with Axol's easy-to-use protocol | 20 days |
| Cortical inhibitory interneurons | Ideal for use in co-culture methodologies for AD, seizure and epilepsy studies | 20 days |
| Striatal neurons | Ideal for use in models of HD. Supplied as NSCs, with maturation to striatal neurons using Axol's easy-to-use protocol | 21 days |
| Motor neurons | Ideal for use in in vitro models of ALS with muscle cells (myotubes) | 31 days |
| Microglia | Ideal for use in co-culture with neurons for AD and ALS research / monoculture for compound screening | 10 days |
| Astrocytes | Ideal for use in co-culture with neurons for AD and ALS research | 5 days |
| Myotubes | Ideal for use in neuromuscular research including ALS / models of the neuromuscular junction | 7 days |
| Sensory neurons | Ideal for use in cosmetic sensitisation testing and pain models | 2 days |
| Ventricular cardiomyocytes | Ideal for use in in vitro cardiotoxicity assays / cardiac research | 7 days |
| Atrial cardiomyocytes | Ideal for use in in vitro cardiotoxicity assays / cardiac arrhythmia research | 7 days |
*Manufacture time does not include delivery time
axoCells are designed with co-culture in mind
While monoculture models are valuable for iPSC-based research and drug discovery, advancing to co-culture models can provide deeper insights, greater human relevance, and enhanced data quality, making them a crucial addition to in vitro research projects. Co-culture models use two or more iPSC-derived cell types in an in vitro setting, allowing researchers to incorporate greater complexity, cell-cell interactions, and a more accurate representation of the in vivo environment.
As iPSC experts, Axol Bioscience understand that establishing and executing co-culture models can seem technically challenging. Therefore, we offer our expertise to help neurodegenerative and cardiac researchers harness the benefits of iPSC-based co-culture models. By developing single medias that support multiple cell types, we are preparing our cells for the future of co-culture applications.
Applications
- Drug discovery
- Toxicology
- Regenerative medicine
- Genetic studies
- Personalised medicine
- Developmental biology
- 3D culture and organoids
- Immunology
Materials available for download
Axol Bioscience 2024 catalog
External validation of axoCells ventricular cardiomyocytes
Products
Note: product availability depends on country - see product detail page.
