£323.00
Estimated delivery Fri 17 May
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
443919-96-8
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
536.6
Alternative Names:
3-[[3-fluoro-5-(tetrahydro-4-methoxy-2h-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-1h-pyrazole
- Data sheet: View or download
- MSDS: View or download
Product Description:
CAY10416 is a dual COX-2/5-LO inhibitor with IC50 values of 50 and 3 nM, respectively.{10003} The selectivity of CAY10416 for COX is greater than 200-fold for COX-2 versus COX-1. COX-2/5-LO inhibitors such as CAY10416 are also apoptosis-inducing agents and are potentially useful in prostate cancer chemotherapy. In the PC3 human carcinoma cell line, CAY10416 exhibits a 45% inhibition of proliferation at 100 µM. In the LNCaP human carcinoma cell line, CAY10416 inhibits growth with an IC50 value of 83 µM.
Storage Temperature:
-20°C
