£284.00
Estimated delivery Fri 17 May
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
51803-78-2
Purity:
≥99%
Formulation:
A crystalline solid
Molecular Weight:
308.3
Alternative Names:
n-(4-nitro-2-phenoxyphenyl)-methanesulfonamide, r805
- Data sheet: View or download
- MSDS: View or download
Product Description:
An NSAID and COX2 inhibitor (IC50s = 1.27 and 0.03 µM for the human and ovine enzymes, respectively); selective for COX-2 over COX-1 (IC50s = 70 and 22 µM for the human and ovine enzymes, respectively); inhibits B0AT1 (IC50 = 23 µM for the rat kidney transporter); inhibits infection-induced increases in brain PGE2 levels, and reduces pyresis (ED50 = 0.3 mg/kg), in yeast-infected rats; inhibits formalin-induced hindpaw thermal hyperalgesia in rats at 2.9 mg/kg
Storage Temperature:
-20°C