N-(3-pyridyl)-Indomethacin amide
Catalogue number:
CAY70274-10 mg
Supplier:
Size:
10 mg _$$_
Product is available in:
£168.00
Estimated delivery Fri 10 May
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
261766-29-4
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
433.9
Alternative Names:
n-(3-pyridyl)-1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1h-indole-3-acetamide, n-3pyia
- Data sheet: View or download
- MSDS: View or download
Product Description:
N-3PyIA is one of several aromatic amides of indomethacin reported to be potent and selective reversible inhibitors of COX-2.{8243} N-3PyIA selectively inhibits human recombinant COX-2 with an IC50 of 52 nM. It is about 1,300 times less potent as an inhibitor of ovine COX-1.{8243} However, N-3PyIA does not distinguish between ovine COX-1 and -2. The IC50 values for ovine COX-1 and -2 are 75 and 50 µM, respectively.{8513}
Storage Temperature:
-20°C
