£283.00
Estimated delivery Wed 29 May
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
53126-64-0
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
528.6
Alternative Names:
(2′s,4e,9r,10e,12z,16r,16as,18r,19ar,23ar,25r)-6,7,16,16a,19a,22-hexahydro-25-hydroxy-9-[(1s)-1-hydroxyethyl]-16a,21-dimethyl-spiro[5,9:16,18-dimethano-1h,3h,23h-[1,6,12]trioxacyclooctadecino[3,4-d][1]benzopyran-17(18h),2′-oxirane]-3,14(9h)-dione
- Data sheet: View or download
- MSDS: View or download
Product Description:
A trichothecene mycotoxin; induces production of ROS, increases in MDA levels, and apoptosis in PC12 cells from 5-100 nM; cytotoxic to HUVECs (IC50 = 6.8 ng/ml), as well as HepG2, A549, A204, U937, and Jurkat cancer cells (IC50s = 1.2-3.4 ng/ml); induces ulceration of the small intestine in, and is lethal to mice (LD50 = 5.69 mg/kg)
Storage Temperature:
-20°C
