PD 0325901
Catalogue number:
CAY13034-10 mg
Supplier:
Size:
10 mg
Product is available in:
£102.00
Estimated delivery Wed 7 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
391210-10-9
Purity:
≥90%
Formulation:
A crystalline solid
Molecular Weight:
482.2
Alternative Names:
n-[(2r)-2,3-dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-benzamide
- Data sheet: View or download
- MSDS: View or download
Product Description:
A potent MEK inhibitor that suppresses phosphorylation of ERK in murine colon 26 tumors with an IC50 value of 0.33 nM; suppression of ERK activation with 1 µM PD 0325901 combined with 3 µM CHIR99021 (a glycogen synthase kinase-3 inhibitor) prevents cell differentiation and sustains self renewal of mouse embryonic stem cells for at least eight passages
Storage Temperature:
-20°C