£42.00
Estimated delivery Wed 8 May
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
58546-54-6
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
416.5
Alternative Names:
(6s,7s,13ar)-5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-benzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-6-ol, besigomsin, gomisin a, wuweizichun b
- Data sheet: View or download
- MSDS: View or download
Product Description:
A lignan with hepatoprotective activity; increases the expression of the PXR target genes Cyp3a11, Ugt1a1, Oatp2, and Mrp3 in mouse liver and CYP3A4, UGT1A1, and OATP2 in HEK293T cells; protects against lithocholic acid-induced hepatic necrosis and intrahepatic cholestasis in wild-type, but not Pxr-null, mice; decreases mortality in a mouse model of cholestasis at 100 mg/kg twice per day
Storage Temperature:
-20°C
