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Anti-Aurora B Rabbit Monoclonal Antibody

Supplier:
Catalogue number:
A1606-50
Size:
50 µl
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£377.00 Estimated delivery Wed 28 Apr
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The serine/threonine protein kinase aurora B (Aurora B) is a chromosomal passenger protein critical for accurate chromosome segregation, cytokinesis, protein localisation to the centromere and kinetochore, correct microtubule-kinetochore attachment, and regulation of the mitotic checkpoint. Aurora B forms a tight complex with inner centrosome protein and survivin. Inactivation of any of these proteins causes similar defects in chromosome segregation. A significant overexpression of Aurora B has been found in a variety of human tumors including non-small cell lung carcinoma, astrocytoma, seminoma and carcinomas of the colon, prostate, endometrium and thyroid. The expression level of Aurora B is associated with cell proliferation and prognosis in these tumors.

Product Type:

Antibodies

Species Reactivity:

Human

Storage Temp:

-20°C

Antibody Host:

Rabbit

Antibody Isotype:

Rabbit IgG

Formulation:

In 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

Antibody Type:

Monoclonal

Clone Number:

RM278

UNSPSC Code:

12352203

Anti-Aurora B Rabbit Monoclonal Antibody

Anti-Aurora B Rabbit Monoclonal Antibody