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Anti-BAF53B Antibody

Supplier:
Catalogue number:
A1620-100
Size:
100 µl
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£377.00 Estimated delivery Wed 28 Apr
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Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex), as such plays a role in remodeling mononucleosomes in an ATP-dependent fashion, and is required for postmitotic neural development and dendritic outgrowth. During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes.

Product Type:

Antibodies

Species Reactivity:

Human, Mouse, Rat

Storage Temp:

-20°C

Antibody Host:

Rabbit

Antibody Isotype:

Rabbit IgG

Formulation:

In 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol and 0.01% sodium azide

Antibody Type:

Polyclonal

UNSPSC Code:

12352203

Anti-BAF53B Antibody

Anti-BAF53B Antibody