Gemcitabine (hydrochloride)
Catalogue number:
CAY9003096-100 mg
Supplier:
Size:
100 mg _$$_
Product is available in:
£330.00
Estimated delivery Tue 14 May
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
122111-03-9
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
299.7
Alternative Names:
2'-deoxy-2',2'-difluoro-cytidine, monohydrochloride, ddfc, dfdc, ly 188011
- Data sheet: View or download
- MSDS: View or download
Product Description:
An active metabolite of NUC-1031 and gemcitabine elaidate and a prodrug form of gemcitabine di- and triphosphates; cytotoxic to HepG2 and A549 cells (IC50s = 5.2 and 16 nM, respectively); inhibits tumor growth in various breast, colon, lung, and pancreatic cancer mouse xenograft models; sensitizes tumors to PD-1-targeting antibodies, decreases the number of tumor-infiltrating Tregs, and increases survival in an MC-38 syngeneic mouse model of colon carcinoma at 12 mg/kg
Storage Temperature:
-20°C
