(+)-D-threo-PDMP (hydrochloride)
Catalogue number:
CAY10178-10 mg
Supplier:
Size:
10 mg _$$_
Product is available in:
£608.00
Estimated delivery Wed 22 May
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
139889-62-6
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
427
Alternative Names:
n-[(1r,2r)-2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-decanamide, monohydrochloride, d-pdmp
- Data sheet: View or download
- MSDS: View or download
Product Description:
A glucosylceramide synthase inhibitor; inhibits glucosylceramide synthase by 50% at a 5 µM in an enzyme assay; the active component of racemic DL-threo-PDMP; inhibits the synthesis of glucosylceramide synthase and lactosylceramide in B16 melanoma cells at 25 µM; inhibits B4GALT6 and prevents lactosylceramide synthesis; inhibits ganglioside biosynthesis, reduces long-term potentiation (LTP) in mouse hippocampal CA1 neurons, and impairs learning in the four-pellet taking test in mice
Storage Temperature:
-20°C
