£139.00
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
872365-14-5
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
426.4
Alternative Names:
2-methyl-1-[[4-(methylsulfonyl)-2-(trifluoromethyl)phenyl]methyl]-1 h -pyrrolo[2,3b]pyridine-3-acetic acid, nvp-qaw039, qaw039
- Data sheet: View or download
- MSDS: View or download
Product Description:
A DP2/CRTH2 antagonist (Ki = 1.05 nM); reduces PGD2-induced eosinophil shape change (IC50s = 0.4 and 0.44 nM for isolated human eosinophils and human whole blood, respectively); inhibits PGD2-induced release of IL-5 and IL-13 in isolated human CD4+) Th2 cells (IC50s = 2.56 and 1.4 nM, respectively); reduces the number of BALF eosinophils in a mouse model of asthma (ED50 = ~1 mg/kg)
Storage Temperature:
-20°C
