£1516.00
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1197958-12-5
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
529
Alternative Names:
5-chloro-n2-[4-[4-(dimethylamino)-1-piperidinyl]-2-methoxyphenyl]-n4-[2-(dimethylphosphinyl)phenyl]-2,4-pyrimidinediamine
- Data sheet: View or download
- MSDS: View or download
Product Description:
A potent inhibitor of ALK (IC50 = 0.07 nM) that is less effective at IGF-1R and InsR (IC50s = 3.2 and 100 nM, respectively); drives cell death in (ALK+) Karpas-299 lymphoma cells with an IC50 value of 41.5 nM, while killing (ALK-) U937 cells with an IC50 value of 1,718 nM
Storage Temperature:
-20°C
