In one study where this peptide was labeled with 125I, it was found to bind specifically and with high affinity to αvβ3 receptors on neovascular blood vessel sections of different major humanCancers. The integrin alpha(IIb)beta(3)-specific cyclic hexapeptide contains an Arg-Gly-Asp (RGD) sequence.
Proteins & Peptides
Peak Area by HPLC ≥95%
Van Hagen, PM. et al. Int. J. Cancer 90, 186 (2000); Hu, B. et al. Biochem. 39, 2284 (2000).