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HIV Substrate, HiLyte™ Fluor 488 - ANA60635 - 0.1 mg - AnaSpec - proteins & peptides

HIV Substrate, HiLyte™ Fluor 488
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Size: 0.1 mg
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HIV Substrate, HiLyte™ Fluor 488

Ths is a HiLyte Fluor labeled HIV protease substrate I, GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS. The peptide sequence is derived from the native p17/p24 cleavage site on HIV precursor polyprotein Prgag for HIV-1 protease. Cleavage of HIV precursor polyproteins is essential for the maturation of the infectious virus and hence the protease has become a major target for developing anti-AIDS drugs. The peptide substrate is widely used for the continuous assay for HIV protease activity. The QXL/488 pair offers better sensitivity in detection at a higher wavelength with less background interference. (Excitation/Emission = 490 nm/520 nm).

Product Type:
Proteins & Peptides
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Compound Purity:
Peak Area by HPLC ≥95%
Molecular Weight:
1, Seelmeier S, et al. Proc. Natl. Acad. Sci. USA 85, 6612 (1988). 2, Schneider J, and Kent SBH. Cell 54, 363 (1988). 3, Gehringer H et al. J. Virol. Methods 109, 143 (2003).
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