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HIV Substrate, HiLyte™ Fluor 488

Supplier:
Catalogue number:
ANA60635
Size:
0.1 mg
Product is available in:
  • UK
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Ths is a HiLyte Fluor labeled HIV protease substrate I, GABA-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-EDANS. The peptide sequence is derived from the native p17/p24 cleavage site on HIV precursor polyprotein Prgag for HIV-1 protease. Cleavage of HIV precursor polyproteins is essential for the maturation of the infectious virus and hence the protease has become a major target for developing anti-AIDS drugs. The peptide substrate is widely used for the continuous assay for HIV protease activity. The QXL/488 pair offers better sensitivity in detection at a higher wavelength with less background interference. (Excitation/Emission = 490 nm/520 nm).

Product Type:

Proteins & Peptides

Storage Temp:

-20°C

Compound Purity:

Peak Area by HPLC ≥95%

Molecular Weight:

2008.1

Reference:

1, Seelmeier S, et al. Proc. Natl. Acad. Sci. USA 85, 6612 (1988). 2, Schneider J, and Kent SBH. Cell 54, 363 (1988). 3, Gehringer H et al. J. Virol. Methods 109, 143 (2003).

UNSPSC Code:

12352202