STO-609 (acetate)
Catalogue number:
CAY15325-1 mg
Supplier:
Size:
1 mg _$$_
Product is available in:
£42.00
Estimated delivery Wed 8 May
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1173022-21-3
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
374.4
Alternative Names:
7-oxo-7h-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid, monoacetate
- Data sheet: View or download
- MSDS: View or download
Product Description:
A CaMKK inhibitor (IC50s = 120 and 40 ng/ml for CaMKKα and CaMKKβ, respectively); selective for CaMKKs over CaMKI, CaMKII, CaMKIV, MLCK, PKC, PKA, and p42 MAPK (IC50s = ≥ 10,000 ng/ml for all); inhibits phosphorylation of CaMKI and AMPK in chicken sperm in the presence of extracellular calcium, as well as reduces chicken sperm motility; decreases Npy and Agrp expression and cumulative food intake in mice at 20 µM 0.5 µL/hour, i.c.v.; increases cortical, striatal, and total infarct volume in a mouse model of MCAO-induced focal transient cerebral ischemia at 3 µg/animal, i.c.v.
Storage Temperature:
-20°C
