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STO-609

Catalogue number:
CAY31358-5 mg
Supplier:
Size:
5 mg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£140.00 Estimated delivery Tue 9 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

52029-86-4

Purity:

≥95% (mixture of isomers)

Formulation:

A solid

Molecular Weight:

314.3

Alternative Names:

7-oxo-7h-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid

Product Description:

A CaMKK inhibitor (IC50s = 120 and 40 ng/ml for CaMKKα and CaMKKβ, respectively); selective for CaMKKs over CaMKI, CaMKII, CaMKIV, MLCK, PKC, PKA, and p42 MAPK (IC50s = ≥ 10,000 ng/ml for all); inhibits phosphorylation of CaMKI and AMPK in chicken sperm in the presence of extracellular calcium, as well as reduces chicken sperm motility; decreases Npy and Agrp expression and cumulative food intake in mice at 20 µM 0.5 µL/hour, i.c.v.; increases cortical, striatal, and total infarct volume in a mouse model of MCAO-induced focal transient cerebral ischemia at 3 µg/animal, i.c.v.

Storage Temperature:

-20°C

Details Cat number & supplier Size Price
STO-609 (acetate) CAY15325-1 mg · Cayman Chemical
CAY15325-1 mg
Cayman Chemical
1 mg £42.00
1 mg
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