*

Biotin-ACTH (1-39), human

Supplier:
Catalogue number:
ANA23968
Size:
0.5 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£328.00 Shipping is calculated in checkout

This C-terminally labeled biotin ACTH (1-39) has been used in ELISA assays. Adrenocorticotropic hormone (ACTH), also known as corticotropin, is a cleavage product from a larger precursor proopiomelanocortin (POMC). This 39 amino acid-peptide hormone is produced in the anterior pituitary gland upon stimulation by the corticotropin releasing hormone from the hypothalamus in response to stress. It stimulates the secretion of steroid hormone, specifically glucocorticoids in the adrenal cortex by acting through a cell membrane receptor (ACTH-R). In mammals, the action of ACTH is limited to those areas of the adrenal cortex in which the glucocorticoid hormones cortisol (hydrocortisone) and corticosterone are formed. ACTH has little control over the secretion of aldosterone, the other major steroid hormone from the adrenal cortex.

Product Type:

Proteins & Peptides

Storage Temp:

-20°C

Compound Purity:

Peak Area by HPLC ≥95%

Molecular Weight:

4768.4

Reference:

Moreno-Guzmán, M. et al. Biosensors Bioelectronics 35, 82 (2012). doi: 10.1016/j.bios.2012.02.015Stewart, PM. et al. Clin Endocrinol 40, 199 (1994)Elias, LL. and AJ. Clark, Braz J Med Biol Res 33, 1245 (2000)Latronico, AC. Braz J Med Biol Res 33, 1249 (2000)

UNSPSC Code:

12352202

Sorry - there are no images available for this product.