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Irinotecan

Supplier:
Catalogue number:
i6932-250 mg
Size:
250 mg
Product is available in:
  • UK
  • Ireland
  • Europe
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  • Rest of World
£705.00 Estimated delivery Tue 28 Sep
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Camptothecin analog; topoisomerase I inhibitor, potential AChE inhibitor.

Product Type:

Biochemicals

CAS Number:

97682-44-5

Storage Temp:

4°C

Compound Purity:

≥98%

Molecular Weight:

586.68

Reference:

Hu J, Kinn J, Zirakzadeh AA, et al. The effects of chemotherapeutic drugs on human monocyte-derived dendritic cell differentiation and antigen presentation. Clin Exp Immunol. 2013 Jun;172(3):490-9. PMID: 23600838. Pan P, Li Y, Yu H, et al. Molecular principle of topotecan resistance by topoisomerase I mutations through molecular modeling approaches. J Chem Inf Model. 2013 Apr 22;53(4):997-1006. PMID: 23521602. Chen AY, Chen PM, Chen YJ. DNA topoisomerase I drugs and radiotherapy for lung cancer. J Thorac Dis. 2012 Aug;4(4):390-7. PMID: 22934142. Chintala S, Tóth K, Cao S, et al. Se-methylselenocysteine sensitizes hypoxic tumor cells to irinotecan by targeting hypoxia-inducible factor 1alpha. Cancer Chemother Pharmacol. 2010 Oct;66(5):899-911. PMID: 20066420. Dodds HM, Rivory LP. The mechanism for the inhibition of acetylcholinesterases by irinotecan (CPT-11). Mol Pharmacol. 1999 Dec;56(6):1346-53. PMID: 10570064.

Structure:

C33H38N4O6

Formula:

C33H38N4O6

UNSPSC Code:

12352200

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