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Carnosol

Supplier:
Catalogue number:
c0267-25 mg
Size:
25 mg
Product is available in:
  • UK
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£793.00 Estimated delivery Tue 28 Sep
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Diterpene compound originally found in Rosmarinus; PGE2 synthase inhibitor.

Product Type:

Biochemicals

CAS Number:

5957-80-2

Alternative Names:

CCRIS 7122

Storage Temp:

-20°C

Compound Purity:

≥98%

Molecular Weight:

330.42

Reference:

Vergara D, Simeone P, Bettini S, et al. Antitumor activity of the dietary diterpene carnosol against a panel of human cancer cell lines. Food Funct. 2014 Jun 28;5(6):1261-9. PMID: 24733049. Park KW, Kundu J, Chae IG, et al. Carnosol induces apoptosis through generation of ROS and inactivation of STAT3 signaling in human colon cancer HCT116 cells. Int J Oncol. 2014 Apr;44(4):1309-15. PMID: 24481553. López-Jiménez A, García-Caballero M, Medina MÁ, et al. Anti-angiogenic properties of carnosol and carnosic acid, two major dietary compounds from rosemary. Eur J Nutr. 2013 Feb;52(1):85-95. PMID: 22173778. Machado DG, Cunha MP, Neis VB, et al. Antidepressant-like effects of fractions, essential oil, carnosol and betulinic acid isolated from Rosmarinus officinalis L. Food Chem. 2013 Jan 15;136(2):999-1005. PMID: 23122155. Bauer J, Kuehnl S, Rollinger JM, et al. Carnosol and carnosic acids from Salvia officinalis inhibit microsomal prostaglandin E2 synthase-1. J Pharmacol Exp Ther. 2012 Jul;342(1):169-76. PMID: 22511203. Mengoni ES, Vichera G, Rigano LA, et al. Suppression of COX-2, IL-1β and TNF-α expression and leukocyte infiltration in inflamed skin by bioactive compounds from Rosmarinus officinalis L. Fitoterapia. 2011 Apr;82(3):414-21. PMID: 21129455. Johnson JJ, Syed DN, Suh Y, et al. Disruption of androgen and estrogen receptor activity in prostate cancer by a novel dietary diterpene carnosol: implications for chemoprevention. Cancer Prev Res (Phila). 2010 Sep;3(9):1112-23. PMID: 20736335.

Structure:

C20H26O4

Formula:

C20H26O4

UNSPSC Code:

12352200

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