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Bisacodyl

Supplier:
Catalogue number:
b3374-25 g
Size:
25 g
Product is available in:
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£150.00 Estimated delivery Tue 5 Oct
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Diphenylmethane derivative, stimulates colonic muscle contractions; Na+/K+ ATPase inhibitor.

Product Type:

Biochemicals

CAS Number:

603-50-9

Alternative Names:

Bicol, Broxalax, Contalax, DAMP, Dulrolax, Endokolat, Laxadin, Laxorex, Perilax, Telemin, Ulcolax

Storage Temp:

4°C

Compound Purity:

≥98%

Molecular Weight:

361.39

Reference:

Ikarashi N, Baba K, Ushiki T, et al. The laxative effect of bisacodyl is attributable to decreased aquaporin-3 expression in the colon induced by increased PGE2 secretion from macrophages. Am J Physiol Gastrointest Liver Physiol. 2011 Nov;301(5):G887-95.PMID: 21868635. Manabe N, Cremonini F, Camilleri M, et al. Effects of bisacodyl on ascending colon emptying and overall colonic transit in healthy volunteers. Aliment Pharmacol Ther. 2009 Nov 1;30(9):930-6. PMID: 19678812. Beubler E, Schirgi-Degen A. Stimulation of enterocyte protein kinase C by laxatives in-vitro. J Pharm Pharmacol. 1993 Jan;45(1):59-62. PMID: 8094448.

Structure:

C22H19NO4

Formula:

C22H19NO4

UNSPSC Code:

12352200

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