RU-SKI 43 (hydrochloride)
Catalogue number:
HY-18366A-50mg
Supplier:
Size:
50 mg
Product is available in:
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1782573-67-4
Purity:
99.55
Molecular Weight:
423.01
- Data sheet: View or download
- MSDS: View or download
- Protocol: View or download
Product Description:
RU-SKI 43 hydrochloride is a potent and selective Hedgehog acyltransferase (Hhat) inhibitor with an IC50 of 850 nM. RU-SKI 43 hydrochloride reduces Gli-1 activation through Smoothened-independent non-canonical signaling and decreases Akt and mTOR pathway activity. RU-SKI 43 hydrochloride has anti-cancer activity[1].
Storage Temperature:
4°C (Powder, sealed storage, away from moisture)