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AF-DX 116

Supplier:
Catalogue number:
CAY30871-5 mg
Size:
5 mg
Product is available in:
  • UK
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£101.00 Estimated delivery Thu 24 Jun
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A muscarinic M2 receptor antagonist (Ki = 0.2 µM); selective for cardiac M2 over salivary gland M3 receptors (Ki = 5.01 µM) but also binds sympathetic ganglia M1 receptors (Ki = 0.81 µM); increases vagus nerve stimulation-induced increases in perfusion pressure by 50% in isolated perfused rat hearts at 0.1 µM; increases systolic blood pressure and heart rate in a rat model of hypotension induced by repeated cold stress at 50, 100, and 200 µg/kg

Product Type:

Biochemicals

CAS Number:

102394-31-0

Alternative Names:

11-[2-[2-[(diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-6h-pyrido[2,3-b][1,4]benzodiazepin-6-one

Storage Temp:

-20°C

Formulation:

A solid

Compound Purity:

≥98%

UNSPSC Code:

12352200

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