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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
102394-31-0
Purity:
≥98%
Formulation:
A solid
Molecular Weight:
421.5
Alternative Names:
11-[2-[2-[(diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-6h-pyrido[2,3-b][1,4]benzodiazepin-6-one
- Data sheet: View or download
- MSDS: View or download
Product Description:
A muscarinic M2 receptor antagonist (Ki = 0.2 µM); selective for cardiac M2 over salivary gland M3 receptors (Ki = 5.01 µM) but also binds sympathetic ganglia M1 receptors (Ki = 0.81 µM); increases vagus nerve stimulation-induced increases in perfusion pressure by 50% in isolated perfused rat hearts at 0.1 µM; increases systolic blood pressure and heart rate in a rat model of hypotension induced by repeated cold stress at 50, 100, and 200 µg/kg
Storage Temperature:
-20°C