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Remdesivir

Several clinical studies have highlighted the potential role of remdesivir (GS-5734), as an effective SARS-CoV-2 antiviral drug. Studies examining the pharmacological and human safety profile of remdesivir will enable the preclinical and clinical evaluation of these drugs for the treatment of COVID-19.

Cambridge Bioscience offers a wide range of sizes of high purity remdesivir with short lead-times from our partners Cayman Chemical, MedChemExpress and Biovision.

Remdesivir

Remdesivir (GS-5734), a nucleoside analogue with effective antiviral activity.

Remdesivir references
Agostini ML, et al. Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease. MBio. 2018 Mar 6;9(2). pii: e00221-18.

Wang M, et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res. 2020 Mar;30(3):269-271.

Riva, L., Yuan, S., Yin, X. et al. Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing. Nature (2020).

Thi Nhu Thao T, Labroussaa F, Ebert N, et al. Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform. Nature. 2020;582(7813):561-565. doi:10.1038/s41586-020-2294-9

Ko M, Jeon S, Ryu WS, Kim S. Comparative analysis of antiviral efficacy of FDA-approved drugs against SARS-CoV-2 in human lung cells [published online ahead of print, 2020 Aug 7]. J Med Virol. 2020;10.1002/jmv.26397.

Yin W, Mao C, Luan X, et al. Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir. Science. 2020;368(6498):1499-1504.

Yuan S, Chan CC, Chik KK, et al. Broad-Spectrum Host-Based Antivirals Targeting the Interferon and Lipogenesis Pathways as Potential Treatment Options for the Pandemic Coronavirus Disease 2019 (COVID-19). Viruses. 2020;12(6):628. Published 2020 Jun 10

Parang K, El-Sayed NS, Kazeminy AJ, Tiwari RK. Comparative Antiviral Activity of Remdesivir and Anti-HIV Nucleoside Analogs Against Human Coronavirus 229E (HCoV-229E). Molecules. 2020;25(10):2343. Published 2020 May 17

Please note that these products are for in vitro laboratory research use only and are not suitable for human consumption or veterinary diagnostic or therapeutic use.

Products

Note: product availability depends on country - see product detail page.

Details Cat number & supplier Size Price
Remdesivir CAY30354-5 mg · Cayman Chemical
CAY30354-5 mg
Cayman Chemical
5 mg £1089.00
5 mg
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Remdesivir CAY30354-10 mg · Cayman Chemical
CAY30354-10 mg
Cayman Chemical
10 mg £187.00
10 mg
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Remdesivir CAY30354-50 mg · Cayman Chemical
CAY30354-50 mg
Cayman Chemical
50 mg £654.00
50 mg
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Remdesivir CAY30354-100 mg · Cayman Chemical
CAY30354-100 mg
Cayman Chemical
100 mg £1058.00
100 mg
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Remdesivir HY-104077-1mg · MedChem Express
HY-104077-1mg
MedChem Express
1 mg £224.00
1 mg
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Remdesivir HY-104077-5mg · MedChem Express
HY-104077-5mg
MedChem Express
5 mg £561.00
5 mg
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Remdesivir HY-104077-10mg · MedChem Express
HY-104077-10mg
MedChem Express
10 mg £867.00
10 mg
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Remdesivir HY-104077-1mL · MedChem Express
HY-104077-1mL
MedChem Express
10 mM/1 ml £743.00
10 mM/1 ml
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Remdesivir B2997-500 · BioVision
B2997-500
BioVision
500 µg £249.00
500 µg
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Remdesivir B2997-1000 · BioVision
B2997-1000
BioVision
1 mg £422.00
1 mg
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