£1338.00
Estimated delivery Tue 30 Apr
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1809249-37-3
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
602.6
Alternative Names:
n-[(s)-hydroxyphenoxyphosphinyl)-l-alanine, 2-ethylbutyl ester, 6-ester with 2-c-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-d-altrononitrile, gs-5734
- Data sheet: View or download
- MSDS: View or download
- Related Content: Remdesivir
Product Description:
A prodrug form of GS-443902; reduces viral titers in primary HAE cells infected with MERS-CoV or SARS-CoV (EC50s = 0.074 and 0.069 µM, respectively); reduces infectious virus production in SARS-CoV-2-infected HAE cells (EC50 = 10 nM); reduces lung viral titers and prevents weight loss in a mouse model of SARS-CoV infection at 25 and 50 mg/kg; reduces lung viral titer and lung hemorrhage and improves pulmonary function in mice infected with a chimeric SARS-CoV encoding the SARS-CoV-2 RdRp at 25 mg/kg
Storage Temperature:
-20°C