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Small GTPase Activation Assays, Western Blot Citation List

Arf Activation Assays

Casey, C.A. et al. (2016). Study of ethanol-induced Golgi disorganization reveals the potential mechanism of alcohol-impaired N-glycosylation. Alcoholism: Clin. and Exp. Res. doi:10.1111/acer-13247

Fischer. A. et al (2016). AKT-dependent phosphorylation of the SAM domain induces oligomerization and activation of the scaffold protein CNK1. Biochimica et Biophysica Acta - Mol. Cell Res. 1864:89-100 (#STA-407-1). (#STA-407-1)

Matsumoto, Y. et al. (2016). Inhibition of epitehlial-mesenchymal transition by cetuximab via the EGFR-GEP100-Arf6-AMAP1 pathway in head and neck cancer. Head Neck doi:10.1002/hed.24626 (#STA-407-6).

Dutta, D. & Donaldson, J. G.  (2015). Sorting of clathrin‐independent cargo proteins depends on Rab35 delivered by clathrin‐mediated endocytosis. Traffic. doi: 10.1111/tra.12302 (#STA-407-6).

Cheung, H. N. et al. (2014). FE65 interacts with ADP-ribosylation factor 6 to promote neurite outgrowth. FASEB J.  28:337-349 (#STA-407-6).


Cdc42 Activation Assays

Hong, J. H. et al. (2016). Regulation of the actin cytoskeleton by the Ndel1-Tara complex is critical for cell migration. Sci Rep. doi:10.1038/srep31827 (#STA-402).

Aldinucci, A. et al. (2016). Histamine regulates actin cytoskeleton in human Toll like receptor 4 activated monocyte derived dendritic cells tuning CD4+ T lymphocyte response. J Biol Chem. doi:10.1074/jbc.M116.720680 (#STA-402).

Prudent, J. et al. (2016). Mitochondrial Ca2+ uptake controls actin cytoskeleton dynamics during cell migration. Sci. Rep. 6:36570 (#STA-405).

Le, L. T. et al. (2016). Loss of miR-203 regulates cell shape and matrix adhesion through ROBO1/Rac/FAK in response to stiffness. J Cell Biol. 212:707-719 (#STA-405).

Sherchan, P. et al. (2015). Recombinant Slit2 attenuates neuroinflammation after surgical brain injury by inhibiting peripheral immune cell infiltration via Robo1-srGAP1 pathway in a rat model. Neurobiol Dis. 85:164-173 (#STA-402).


Rac Activation Assays

Zeng, C. et al. (2016). Leucine-rich repeat kinase-1 regulates osteoclast function by modulating RAC1/Cdc42 small GTPase phosphorylation and activation. Am. J. Physiol. Endocrinol. Metab. 311:E772-E780 (#STA-401-1).

Li, W. et al. (2016). Simvastatin inhibits glucose uptake activity and GLUT4 translocation through suppression of the IR/IRS-1/Akt signaling in C2C12 myotubes. Biomed Pharmacother. doi:10.1016/j.biopha.2016.06.029 (#STA-401-1).

Yoshida, S. et al. (2016). Semaphorin 3A induces odontoblastic phenotype in dental pulp stem cells. J Dent Res. doi:10.1177/0022034516653085 (#STA-401-1).

Kim, S. J. & Yoon, S. (2016). Activated Rac1 regulates the degradation of IκBα and the nuclear translocation of STAT3–NFκB complexes in starved cancer cells. Exp Mol Med. doi:10.1038/emm.2016.17 (#STA-401-1).

Wu, J. et al. (2016). Recombinant osteopontin stabilizes smooth muscle cell phenotype via integrin receptor/integrin-linked kinase/rac-1 pathway after subarachnoid hemorrhage in rats. Stroke. 47:1319-1327 (#STA-401-1).


Ran Activation Assay

Brasseur, A. et al. (2014). The bi-Lobe-Associated LRRP1 Regulates Ran Activity in Trypanosoma brucei. J Cell Sci. 127:4846-4856.

Hakim, A. et al. (2013). Importin-7 mediates glucocorticoid receptor nuclear import and is impaired by oxidative stress, leading to glucocorticoid insensitivity. FASEB J.27:4510-4519.


Rap Activation Assays

Czikora, A. et al. (2016). Structural basis for the failure of the C1 domain of Ras guanine nucleotide releasing protein 2 (RasGRP2) to bind phorbol ester with high affinity. J Biol Chem. 291:11133-11147.

Ishiguro, K. et al. (2014). Suppressive action of acetate on interleukin-8 production via tubulin-α acetylation.  Immunol Cell Biol. 92:624-630.

Monteiro, A.C. et al. (2014).  Trans-dimerization of JAM-A regulates Rap2 and is mediated by a domain that is distinct from the cis-dimerization interface. Mol Biol Cell. 25:1574-1585.


Ras Activation Assays

Nakaoka, H. J. et al. (2016). NECAB3 promotes activation of hypoxia-inducible factor-1 during normoxia and enhances tumourigenicity of cancer cells. Sci Rep.6:22784.

Krencik, R. et al. (2015). Dysregulation of astrocyte extracellular signaling in Costello syndrome.  Sci Transl Med. doi:10.1126/scitranslmed.aaa5645.

Sun, Y. et al. (2014). Reduced miR-3127-5p expression promotes NSCLC proliferation/invasion and contributes to dasatinib sensitivity via the c-Abl/Ras/ERK pathway. Sci Rep. 4:6527.

Hernández-Porras, I. et al. (2014).  K-RasV14I Recapitulates Noonan Syndrome in Mice. Proc Natl Acad Sci U S A. 111:16395-16400.

Gall, J. M. et al. (2014). Conditional Knockout of Proximal Tubule Mitofusin 2 Accelerates Recovery and Improves Survival after Renal Ischemia. J Am Soc Nephrol. 10.1681/ASN.2014010126.


Rho Activation Assays

Ma, J. H. et al. (2016). The role of IRE-XBP1 pathway in regulation of retinal pigment epithelium tight junctionsXBP1 regulates the RPE tight junctions. Invest Ophthalmol Vis Sci. 57:5244-5252 (#STA-403-A).

Kim, J. M. et al. (2016). Distinctive and selective route of PI3K/PKCα-PKCδ/RhoA-Rac1 signaling in osteoclastic cell migration. Mol Cell Endocrinol. doi:10.1016/j.mce.2016.08.042 (#STA-403-A).

Cui, J. et al. (2016). Epigenetic silencing of TPM2 contributes to colorectal cancer progression upon RhoA activation. Tumor Biol. doi:10.1007/s13277-016-5103-1 (#STA-403-A).

Ye, Y. et al. (2016). Down-regulation of 14-3-3 Zeta inhibits TGF-β1–induced actomyosin contraction in human trabecular meshwork cells through rhoa signaling pathway14-3-3 zeta regulates actomyosin contraction in TM cells. Invest Ophthalmol Vis Sci. 57:719-730 (#STA-403-A).

Gayle, S. et al. (2015). piggyBac insertional mutagenesis screen identifies a role for nuclear RhoA in human ES cell differentiation. Stem cell Reports. doi:10.1016/j.stemcr.2015.03.001 (#STA-403-A).