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Palmitoyl Ethanolamide

Catalogue number:
CAY90350-5 mg
Supplier:
Size:
5 mg _$$_
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£42.00 Estimated delivery Tue 30 Jul
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

544-31-0

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Weight:

299.5

Alternative Names:

n-(2-hydroxyethyl)-hexadecanamide, palmidrol, palmityl ethanolamide, pea

Product Description:

An AEA derivative; selectively activates PPARα (EC50 = 3.1 µM) over PPARβ/δ and PPARγ in HeLa cells expressing the human receptors; binds to RBL-2H3 basophil membranes (IC50 = 1 nM), which endogenously express CB2, but not CB1, receptors; inhibits antigen-induced serotonin release from RBL-2H3 cells (EC50 = 0.27 µM); prevents decreases in paw withdrawal latency in a radiant heat hypersensitivity test, an effect that can be reversed by SR141716, GW 9662, and capsazepine, in a mouse model of neuropathic pain induced by chronic constriction injury of the sciatic nerve; decreases carrageenan-induced paw edema in wild-type, but not Ppara-/-, mice at 10 mg/kg; inhibits PTZ-induced tonic convulsions in rats at 40 mg/kg

Storage Temperature:

-20°C

CAY90350-5 mg: Palmitoyl Ethanolamide
CAY90350-5 mg: Palmitoyl Ethanolamide
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